Pathology Annotation Platform

Pathology Annotation Platform for Whole-Slide Images

Annotate whole-slide images (WSI) for histopathology, tissue regions, cells, nuclei, biomarkers, and digital pathology AI with precise segmentation and expert review workflows.

Pathology annotation features

Everything You Need for Complex Pathology Annotation

Work with whole-slide pathology images, move from tissue overview to cellular detail, organize labels with structured ontologies, and accelerate precise annotation with AI-assisted tools.

Whole-slide pathology view with a focused region of interest and cellular-detail inset.
01 · Whole slide

Whole-Slide Image Support

Handle gigapixel whole-slide images natively while preserving full-resolution pathology data.

Whole-slide imagesMulti-resolution zoomRegion navigation
One synthetic pathology specimen shown at overview, region, and cellular-detail resolutions.
02 · Deep zoom

Deep Zoom & Multi-Resolution Viewing

Navigate seamlessly from whole-tissue overview to cellular-level detail across multiple resolution levels.

Dense synthetic fluorescence pathology field with hundreds of structure-aligned instance segmentation masks.
03 · Scale

Annotation at Scale

Create, render, and manage thousands of cells, nuclei, regions, and other annotations across massive pathology slides.

Compact staggered pathology ontology for tissue regions, findings, attributes, relations, and slide properties.
04 · Ontologies

Ontologies

Define nested pathology classes, attributes, relations, and slide-level properties for consistent annotation workflows.

Synthetic pathology field progressing from raw image to a structure-aligned mask and editable pixel-precise boundary.
05 · Segmentation

Pixel-Perfect Segmentation

Precisely delineate cells, nuclei, tumors, tissue regions, and complex microscopic structures at pixel-level accuracy.

Synthetic pathology cells with exact matching masks, a magic cursor, and a prominent Find Similar action.
06 · Automation

AI-Assisted Auto-Labeling

Accelerate pathology annotation with Find Similar, Magic Touch, and automated labeling tools for repetitive structures.

Human reviewAutomated labeling

Built for AI Data at Scale

Annotate complex pathology datasets faster with AI-assisted automation, scalable workflows, and lower operational costs.

10×
Faster pathology data annotation

Batch, Find Similar, Prompt Auto-Labeling, and automated workflows reduce repetitive manual pathology labeling.

90%
Automated pathology annotation

On average, 90% of pathology labels are pre-labeled automatically, then reviewed and refined by humans.

5×
Lower Training Data Costs

The cost per accepted label can be up to 5× lower as curation, annotation, and QA are automated.

Supported pathology annotation types

All pathology annotation types in one platform.

Create regions of interest, tissue segmentation masks, polygons, cell and nuclei instances, point markers, classifications, slide properties, and relations for pathology workflows.

01
Rectangular regions

Bounding Box / ROI

Mark rectangular regions of interest for tissue, tumor, lesion, cell cluster, or review areas.

02
Pixel-level masks

Tissue Segmentation

Capture pixel-level tissue, tumor, lesion, necrosis, or biomarker regions with editable masks.

03
Precise boundaries

Polygon / Tissue Region

Outline irregular tissue regions, tumor margins, glands, and other structures with editable polygons.

04
Pose structures

Cell / Nuclei Instances

Label individual cells and nuclei as distinct instances for detection, counting, and morphology analysis.

05
Paths and edges

Tissue Boundary / Polyline

Trace tissue boundaries, margins, vessels, and elongated structures with connected vertices.

06
Landmark precision

Point / Cell Marker

Mark exact cell centers, nuclei, glands, and other microscopic landmarks on a slide.

07
Oriented volume

Classification / Findings

Assign slide-, region-, or finding-level classes such as tissue type, grade, stain, or biomarker status.

08
Slide-level context

Slide / Item Properties

Label properties that describe the complete slide or item, including source, quality, cohort, and project-specific attributes.

09
Object connections

Relations

Connect findings and tissue regions to capture project-defined contextual relationships.

Pathology annotation quality assurance

Build quality into every pathology annotation.

Compare labels on the same tissue regions, check them against approved references, and resolve issues at the right magnification. Keep expert decisions connected to the original slide evidence.

Independent labels on the same histology region expose an omitted nucleus annotation.
01 · Agreement

Pathology Annotation Consensus

Compare independent labels on the same histology region. Identify omitted nuclei, differing tissue boundaries, and class disagreements for expert review.

Tissue-region evidenceAgreement checksReview disagreements
A nucleus contour extending into cytoplasm is compared with the approved microscopic benchmark.
02 · Benchmarks

Quality Gate (Honeypot)

Check pathology annotations against approved references hidden from annotators. Evaluate supported boundaries and classes using the project's quality criteria.

A review issue connects to a nucleus contour with an instruction to exclude surrounding cytoplasm and a Resolve action.
03 · Validation

Validation & Issue Resolution

Review missing properties and disputed nucleus or tissue boundaries in slide context. Correct the affected annotation and resolve feedback before approval.

Illustrative benchmark and review outcomes for three matching item IDs, including pass, fail, not evaluated, approved, needs rework, and awaiting review.
04 · Insights

Pathology QA Analytics

Track benchmark results, consensus outcomes, and review decisions across slide annotation tasks. Identify recurring issues and focus expert review on difficult regions.

Benchmark resultsReview outcomes
Pathology dataset curation & annotation workflows

Curate pathology data and automate annotation workflows.

Search, version, and inspect pathology datasets, connect AI models, and move annotations through review and approval.

Data Curation Dataset Management
Dataset version control in Unitlab AI for governed medical data releases
Version

Dataset Versions

Create and manage dataset versions as pathology data evolves. Track changes, assign work, and keep every version auditable and production-ready.

Semantic search returning matching medical imaging cases in Unitlab AI
Discover

Semantic Search

Explore large pathology datasets through semantic understanding instead of manual filters. Find relevant cases and slide regions across defined conditions.

Dataset embedding visualization with similar medical and pathology cases and review outliers
Inspect

Embedding View

Visualize dataset structure, identify outliers and labeling issues, and improve pathology-data quality before training.

Integrated medical annotation workflow connecting tumor segmentation, annotation, review, and quality assurance
Orchestrate

Integrated Workflows

Build workflows that connect models, annotation, review, and quality assurance in one continuous loop. Reduce handoffs and keep datasets moving from labeling to approval.

Bring your Pathology model into Unitlab’s annotation workflow
Integrate

Bring Your Pathology Model

Connect your own AI models for pre-labeling and model-assisted annotation. Improve accuracy and iterate faster on real-world pathology datasets.

Questions, answered

Pathology Annotation Platform FAQs

Answers about WSI and histopathology annotation, cells, nuclei, tissue segmentation, digital pathology ontologies, quality workflows, custom models, and dataset operations in Unitlab.

Talk with the Unitlab team
What pathology annotation types does Unitlab support?+

Unitlab supports ROI boxes, tissue segmentation masks, polygons, cell and nuclei instances, point markers, boundaries, classifications, slide properties, and relations. Teams define labels and rules in reusable ontologies for consistent whole-slide image annotation.

Pathology annotation documentation
How does AI-assisted segmentation work in Unitlab?+

Use a built-in or integrated image model to generate a segmentation or polygon prediction, then review and refine the boundary before the annotation moves through quality review.

Auto-annotation documentation
How can reviewers inspect pathology regions consistently?+

Reviewers can inspect the full image and focused regions, compare labels against the ontology, leave issues and comments, and use annotation history to track what was reviewed or corrected.

Annotation review documentation
How do ontologies and properties work in pathology annotation?+

Nested ontologies define classes, classifications, properties, and relations. Class properties describe annotated regions, while slide or item properties capture context that applies to the complete image.

Properties and relations documentation
How does Unitlab manage pathology annotation quality and review?+

Configurable workflows route pathology tasks through annotation, review, rework, and approval. Instructions, assignments, comments, issues, annotation history, dataset versions, and releases keep quality decisions traceable for individual experts and enterprise teams.

Annotation and review documentation
Can teams use their own AI models for pathology pre-labeling?

Yes. Unitlab can bring custom models into the annotation workflow to generate pre-labels and predictions. Annotators review and correct model output instead of starting from zero, while human approval remains part of the governed quality process.

Model integration documentation
Can Unitlab curate, annotate, and version pathology datasets in one platform?

Yes. Teams can curate pathology data with metadata filters, semantic search, embeddings, similarity, and outlier discovery, then annotate selected samples, review results, and publish controlled dataset versions for reproducible AI development.

Dataset management documentation
PATHOLOGY ANNOTATION PLATFORM

Build Production-Ready Pathology Datasets with Unitlab

Annotate, review, and manage complex pathology image data in one AI-assisted workspace. Move from raw images to governed datasets with model-assisted labeling and built-in quality control.